CBC Isolate

Published preclinical research has investigated CBC in the following areas:

Interaction with TRP channels — CBC has been shown to activate TRPA1 and TRPV1 receptors, which are involved in the body's perception of discomfort and temperature signalling.¹

Neurological interest — Preclinical animal studies have explored CBC's potential role in supporting neural stem progenitor cell viability.²

Inflammatory response — In vitro and animal model studies have examined CBC's interaction with inflammatory pathways, including its effects on nitric oxide production and endocannabinoid metabolism (via inhibition of anandamide uptake).³

Topical applications — Researchers have studied CBC alongside other cannabinoids in the context of sebaceous gland function and skin homeostasis.⁴

Entourage interactions — CBC is frequently studied in the context of whole-plant cannabinoid profiles, where researchers examine the combined activity of multiple cannabinoids and terpenes.

References
De Petrocellis, L. et al. (2011). British Journal of Pharmacology, 163(7), 1479–1494.
Shinjyo, N. & Di Marzo, V. (2013). Neurochemistry International, 63(5), 432–437.
DeLong, G.T. et al. (2010). Drug and Alcohol Dependence, 112(1-2), 126–133.
Oláh, A. et al. (2016). Experimental Dermatology, 25(9), 701–707.